Introducing: Nicholas St. Fleur

This is a series of Q&As with new, young and up-and-coming science, health and environmental writers and reporters. They ? at least some of them ? have recently hatched in the Incubators (science writing programs at schools of journalism), have even more recently fledged (graduated), and are now making their mark as wonderful new voices explaining science to the public.

Today we introduce you to Nicholas St. Fleur (blog, Twitter).

Hello and welcome to The SA Incubator. To start off, where are you from?

Hey there! I?m originally from Long Island, New York, but I?m currently upstate in beautiful Ithaca finishing up my senior year at Cornell University.

How did you get into science and how did you get into writing? And how did these two trajectories fuse into becoming a science writer?

Well, I started off my time at Cornell strictly as a biology-premed student, bent on taking only the necessary courses for med school. But my closed mindset opened after a natural disaster occurred winter break of my freshman year ? the 7.0 magnitude earthquake that struck Haiti, the country where my parents were born. Every day on the news I saw medical correspondent Sanjay Gupta report on the devastation, and as sad as it was to watch, I quickly became captivated by the way he combined medicine with media to convey the gravity of the situation. I decided then that I wanted to expand upon my undergraduate interests in science and medicine by learning about journalism, in hopes that I could be like Sanjay Gupta one day. So when classes resumed I enrolled in my first communication course on science, environmental and health reporting.

Though I originally took the course to learn about medical reporting, the class got me hooked on taking complex science news and sharing those stories with a general audience. By the time the semester was done I was eager to learn more about journalism.

So that summer I signed up for a science writing class taught by famed science writer Carl Zimmer at the Cornell-affiliated Shoals Marine Lab, off the coast of Maine. As a part of the class, we spent our days following marine biologists and island ecologists on hagfishing trips and bird-banding brigades, and then wrote articles about our adventures at night. That course was a tough, week-long science writing bootcamp that catapulted me into an undergraduate career chasing science stories for the student newspaper.

Since then I?ve covered diverse science disciplines from solar physics and multi-dimensional mathematics, to plant pathology and environmental activism as a student reporter for The Cornell Daily Sun.

What professional experience have you had so far?publications, internships, jobs? Feel free to include a bunch of links here! What is your current job?

I?m currently the outgoing editor for The Sun?s weekly science section. During my year as head of the science desk, the section has covered cool on-campus research like an engineering team?s work with temporal cloaking, or making moments in time seem invisible, as well as the once-in-a-decade blooming of a titan arum, also known as the rare ?corpse plant.? And yes, it did smell horrendous ? a mix of cabbage gone bad and rotting fish.

But I got the chance to report on science at the professional level this past summer when I had the amazing opportunity to intern at Science as the AAAS Minority Science Writing Intern. I came to Science at an exciting time ? during a summer that saw the announcement of the Higgs Boson discovery and followed by the successful landing of the Curiosity Mars Rover. And though I didn?t get to cover those high-profile science stories, I did get to watch the pros tackle them with hard-hitting reporting and style.

The majority of the stories I wrote fell under the ?creature feature? beat. That means I got to report on exciting new animal research, such as the biomechanics behind the brown-tree snake?s gap-bridging abilities and the unfortunate consequences of noisy housefly sex in a bat-filled cave. I sought out these ?gee whiz? science stories ever since successfully making my first pitch for an article on a carnivorous pitcher plant that uses raindrops to launch unsuspecting insects hiding below its lid into an awaiting acid bath.

Following my summer at Science, I got to attend two major science conferences as a student journalism travel grant recipient. The first was in New Orleans for Neuroscience 2012 where I shadowed Science News neuroscience writer Laura Sanders. Then more recently I was at the AAAS Conference in Boston were I met nine other very talented young science writers from across the country and got to cover a symposium on whale evolution and wrote a piece on the blue whale?s impressive aquatic acrobatics.

Which story of yours do you like best?

That would have to be this story I wrote about where people flee after disaster strikes. The researchers analyzed cell phone data following the 2010 Haiti Earthquake to track down where residents escaping Port-au-Prince went following their exodus from the capital. Through my reporting I heard personal stories about people in Haiti that reflected the results that the researchers had found. It was a very humbling experience to write an article about the same event that had set off my path towards science journalism just a few short years before.

Apart from writing, do you also do other aspects of science communication, e.g., podcasts, video, art/illustration, photography, infographics, or do you do any coding, web design and programming?

At Science I recorded a podcast about Neanderthal extinction theories and artificial jellyfish, and have wanted to do another one ever since. Right now I?m currently working on integrating more multimedia into The Sun?s science agenda. Currently I?ve done the reporting and directing for a few short science films such as this one on the Cornell NYC Tech Campus and this one about a C.U. vet student?s animal activism efforts. Now that I?m done with my editorial position, I?m looking to shoot/produce/edit my own science videos for The Sun, like this one about a biology-inspired student project team called iGem.

I hope to go even further with the science multimedia. After attending ScienceOnline 2013 and meeting online science news personalities like Talk Nerdy to Me?s Cara Santa Maria and Dr. Carin Bondar from Wild Sex and ScienceAlert, I?ve had an itch to start making my own weekly videos that look at a roundup of science news at Cornell.

Do you write a personal or science blog ? How much do you use social media networks, e.g., Twitter, Facebook, Google Plus, Tumblr, Pinterest, Flickr, YouTube etc., to promote your own and your friends? work, to learn and to connect?

Right now Facebook is my main social media platform for broadcasting science news. Throughout the day I tend to post little science ?pick-me ups? to give my friends something interesting to read and ponder while their escaping their studies browsing Facebook. I?ve also taken to Twitter (@SciFleur ? a pun on my last name) and love the rush of live-tweeting science conferences.

I have a portfolio site with an accompanying blog, Stardust; Slightly Used, that I?ve been hesitant to start up. But after attending ScienceOnline and talking with blogging extraordinaires like Bora and Ed Yong I?ve gained some great insight into the world of science blogs. So now, with the proper motivation, some ideas in the pipeline, and interviews already taped on my recorder I?ll be starting my science blog soon ? so stay tuned!

How do you see the current and future science media ecosystem, how it differs from the past, and what role will new, young science communicators like yourself play in building it and making it the best it can be?

Over the past few months I?ve had the good fortune to be able to attend a number of different science journalism conferences, and through these trips I?ve met with many science writers ? some seasoned professionals and others just breaking into the field from grad programs or undergrad. I?ve learned from talking to people across the science communication spectrum that science journalism is changing, and has been for a while. For example, Ivan Oransky gave a presentation at AAAS that showed in 1989 there were over 95 newspapers with science sections, and in 2012 that number had dwindled to 19.

But in its place new tools like blogs, social media and data visualizations have emerged to help inform the public. And in the midst of all this change there is a new generation of science communicators ready to get their messages out. I?ve been lucky enough to have met a good number of them and I can say that the youngins are a talented and driven bunch. The future of science communication will be different, yes, but not lost.? As long as there are scientifically curious people out there, they will find ways to share their stories.

Thank you!

My good sir, thank you!

====================

Previously in this series:

Kristina Ashley Bjoran
Emily Eggleston
Erin Podolak
Rachel Nuwer
Hannah Krakauer
Rose Eveleth
Nadia Drake
Kelly Izlar
Jack Scanlan
Francie Diep
Maggie Pingolt
Jessica Gross
Abby McBride
Natalie Wolchover
Jordan Gaines
Audrey Quinn
Douglas Main
Smitha Mundasad
Mary Beth Griggs
Shara Yurkiewicz
Casey Rentz
Akshat Rathi
Kathleen Raven
Penny Sarchet
Amy Shira Teitel
Victoria Charlton
Noby Leong and Tristan O?Brien
Taylor Kubota
Benjamin Plackett
Laura Geggel
Daisy Yuhas
Miriam Kramer
Ashley Taylor
Kate Yandell
Justine Hausheer
Aatish Bhatia
Ashley Tucker
Jessica Men
Kelly Oakes
Lauren Fuge
Catherine Owsik
Marissa Fessenden
Mollie Bloudoff-Indelicato
Kelly Poe
Kate Shaw
Meghan Rosen
Jon Tennant
Ashley Braun
Suzi Gage
Michael Grisafe
Jonathan Chang
Alison Schumacher
Alyssa Botelho
Hillary Craddock
Susan Matthews
Lacey Avery
Ilana Yurkiewicz
Kate Prengaman

Source: http://rss.sciam.com/click.phdo?i=4af317abd31c405f7b8ac4cd7f75709d

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Filmmaker fights AIDS his way ? Region ? Traverse City Record-Eagle

TRAVERSE CITY ? Max Fisher has a problem.

About two years ago, the Traverse City filmmaker began an AIDS documentary that focuses on the young generation of AIDS activists, but he can?t seem to turn off the camera. Their stories are just too compelling.

?The producer is telling me I need to stop, and I say, ?No. I have to keep recording these amazing stories,? he said. ?If they don?t make it in the movie, they?ll make it somewhere else.?

But at some point, it will be time to ?shut up and edit,? Fisher said.

Fisher has taken the lead of his activist mom, Mary Fisher, who recently appeared on the Today Show to talk about her newest and sixth book, ?Messenger: A Self Portrait.?

Fisher tells her story through the promise she made in her famous speech at the Republican National Convention in 1992: ?I want my children to know that their mother was not a victim. She was a messenger.?

Her poignant, 13-minute speech turned the image of AIDS on its head. Here was a classic beauty and daughter of a prominent Republican family. She worked as the first woman ?advance man? in the Gerald Ford White House. But Mary learned she had contracted AIDS from her husband, whom she divorced in 1991.

She pleaded for a more compassionate world unafraid to say the word AIDS.

?I will not hurry to leave you, my children,? she said. ?But when I go, I pray that you will not suffer shame on my account.?

Max, four at the time, said his mom was prepared to die, but shielded him and his brother from a sense of pending doom. As it turns out, the development of antiretroviral therapies has allowed her a long life.

AIDS awareness became her life?s cause. Her latest message: AIDS medications can?t help the hundreds of thousands who can?t afford them or tolerate the side effects. And there is still no cure. The World Health Organization reported close to 2 million died in 2010.

Max and his brother tested negative for H.I.V., yet lived with its reality every day. Max said his mother was honest about the disease, but never made him fearful.

Mary never thought she?d see Max get married, and breast cancer last year complicated the picture. But last September, she witnessed his marriage vows to Susan Borke.

Max fondly regards Borke as his ?voice of reason? and biggest supporter for FishSoup Films, his full-service film production company. Michael Moore brought the couple together. Fisher worked post-production on Moore?s film, ?Capitalism: A Love Story.? Borke works as an executive assistant for the Traverse City Film Festival, which Moore co-founded.

Max said his mother enthusiastically supports his documentary, yet he is realistic. His mom?s speech was seen by 27 million people. A documentary on pain and dying just won?t have the same pull, he said.

?I don?t ever expect to shine as much as she does,? he said. ?But if I can make even a small impact in one area, I?m happy with that.?

There are still many young people who struggle with shame, particularly those who live in the Bible Belt.

?They don?t want to be ostracized by their church and family so they shrivel up and die, without getting tested,? he said.

?

?

Source: http://record-eagle.com/local/x1746091211/Filmmaker-fights-AIDS-his-way

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Video: Pitbull gives a tour of his hometown Miami

>> and today, he's taking the day off from running his global empire to show off the city he loves.

>> i'm going to show you miami from the other side. i'm going to show you now what inspires me to put out worldwide music. therefore, welcome to the bottom, the magic city , 305. and to the whole world, miami .

>> he was born armando perez to cuban-american parents in little havana .

>> i got to grow up in a city that was growing at the same time. it's like we're both learning together. miami is a melting pot , so many different cultures. you had to learn how to adapt to any environment quick.

>> it's also what kept him grounded. even pitbull says the most important day of his life wasn't the day he got his number one single but the day he got the key to the city .

>> we've come a long way, baby, for real.

>> especially for the boy who used to day dream about living in this house across the water on the exclusive island of key biscayne . look familiar? it was featured in the 1983 al pacino classic "scarface."

>> if i were to ever become the president of the united states of america , i would say washington, d.c., thank you so much. i really appreciate it, the opportunity and the generosity, but that would be my white house right there. and you already know that the secret service agents would definitely look a lot better. yeah.

>> cruising around miami , it would almost seem pitbull is already president, by the legions of fans excited to catch a glimpse of their idol.

>> thank you.

>> but to locals --

>> how are you guys doing?

>> it's not the gold record that is impress them. it's the charitable work pitbull has made his life's mission.

>> we just want to give back to the community but at the same time let them know i'm from the same spot and going through the same struggles.

>> his latest project, building a charter high school called slam in the same neighborhood he grew up for students looking for a career in the sports industry.

>> in no way, shape or form, being raised and growing up in mia miami , i never would have imagined me standing on land of a school that i'm part of. it's emotional for me.

>> clearly it's emotional for these future students as well.

>> someone like pitbull taking an interest in this.

>> it's going to be a great school and the kids that will attend this school could present something that miami could be great.

>> boy, you have a future in politics.

>> and a brighter future for all these students. for their hometown of miami and for their hometown hero .

>> so nice of pitbull to give us a guided tour of miami and just a great guy, too.

>> we love him.

>> i love the concept of scarface.

>> we're all for that. we learned all his --

>> delicious.

>> literally how rich.

Source: http://video.today.msnbc.msn.com/today/50906938/

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Show with Pistorius' dead girlfriend to go ahead

AAA??Feb. 16, 2013?5:46 AM ET
Show with Pistorius' dead girlfriend to go ahead
By GERALD IMRAYBy GERALD IMRAY, Associated Press??

This is an undated portfolio photo supplied by Ice Model Management in Johannesburg of Reeva Steenkamp, during a photo shoot. Paralympic superstar Oscar Pistorius was charged Thursday, Feb. 14, 2013, with the murder of his girlfriend who was shot inside his home in South Africa, a stunning development in the life of a national hero known as the Blade Runner for his high-tech artificial legs. Reeva Steenkamp, a model who spoke out on Twitter against rape and abuse of women, was shot four times in the predawn hours in the home, in a gated community in the capital, Pretoria, police said. (AP Photo/Ice Model Management) EDITORIAL PURPOSE ONLY

This is an undated portfolio photo supplied by Ice Model Management in Johannesburg of Reeva Steenkamp, during a photo shoot. Paralympic superstar Oscar Pistorius was charged Thursday, Feb. 14, 2013, with the murder of his girlfriend who was shot inside his home in South Africa, a stunning development in the life of a national hero known as the Blade Runner for his high-tech artificial legs. Reeva Steenkamp, a model who spoke out on Twitter against rape and abuse of women, was shot four times in the predawn hours in the home, in a gated community in the capital, Pretoria, police said. (AP Photo/Ice Model Management) EDITORIAL PURPOSE ONLY

This is an undated portfolio photo supplied by Ice Model Management in Johannesburg of Reeva Steenkamp, during a photo shoot. Paralympic superstar Oscar Pistorius was charged Thursday, Feb. 14, 2013, with the murder of his girlfriend who was shot inside his home in South Africa, a stunning development in the life of a national hero known as the Blade Runner for his high-tech artificial legs. Reeva Steenkamp, a model who spoke out on Twitter against rape and abuse of women, was shot four times in the predawn hours in the home, in a gated community in the capital, Pretoria, police said. (AP Photo/Ice Model Management) EDITORIAL PURPOSE ONLY

Olympic athlete Oscar Pistorius leaves the Boschkop police station, east of Pretoria, South Africa, Thursday, Feb. 14, 2013. Pistorius was taken into custody after a 30-year-old woman, Reeva Steenkamp, was shot dead at his home. (AP Photo)

JOHANNESBURG (AP) ? South Africa's national broadcaster says it will screen a reality TV show featuring the dead model girlfriend of Oscar Pistorius, two days after she was shot and killed at the home of the double-amputee athlete.

In a statement Saturday, SABC confirms it will air the Tropika Island of Treasure program "which features the late Reeva Steenkamp."

Pistorius has been arrested and charged with the Valentine's Day murder of Steenkamp, who was shot multiple times in the predawn hours of Thursday at Pistorius' house in a gated community in the South African capital, Pretoria.

The show's executive producer, Samantha Moon, tells The Associated Press that Steenkamp's family wants the show to go ahead. Moon says that the family "wants it on. This is how they want to remember her."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-02-16-Pistorius-Girlfriend's%20Show/id-2d6d1e9a613544f8988976e82362b127

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[Q] Google Play Remote install problems

The autoupdate setting has nothing to do with it; I'm experiensing the same issue, the download starts, but it takes 1 minutes before it starts, even if I have Google Play opened on my phone

Quote:

Open Play Store and check your auto update settings. Probably you need to enable it.

If I've helped you, please hit the THANKS button >>>>>>> ?

Source: http://forum.xda-developers.com/showthread.php?t=2149989&goto=newpost

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Streptococcus pneumonia shields foreign DNA derived from other bacteria to promote genetic diversity and vaccine evasion

Streptococcus pneumonia shields foreign DNA derived from other bacteria to promote genetic diversity and vaccine evasion

Friday, February 15, 2013

A new report demonstrates that the human pathogen Streptococcus (S.) pneumoniae (one of the known causes of bacterial pneumonia) possesses an unusual enzyme that protects foreign DNA taken up during transformation, allowing exchange of pathogenicity islands donated from other pathogenic bacteria. This study, published February 14 in the Open Access journal PLOS Pathogens by researchers from the Laboratory of Microbiology and Molecular Genetics (CNRS-Universit? Paul Sabatier, Toulouse, France), establishes a role for this enzyme in protecting internalized DNA from restriction, and simultaneously shows that S. pneumoniaeuses transformation, for example by DNA picked up from other bacterial strains, specifically to promote genome diversification.

Exchange of pathogenicity islands is crucial for pneumococcal virulence, as illustrated by the impressive variability in the polysaccharide capsule, which is usually targeted by current vaccines. Acquisition of different capsule loci, by relying on this genetic transformation, thus allows for vaccine evasion. Natural genetic transformation is thought of as the bacterial equivalent of sexual reproduction, allowing intra- and inter-species genetic exchange. This process, involving uptake of foreign DNA as single-strands (ss) that leads to chromosomal integration, is transient in S. pneumoniae.

Restriction-modification (R-M) systems classically include a restrictase, which protects the host bacteria from attack by bacteriophage via the degradation of only the foreign double-stranded (ds) DNA, and a dsDNA methylase that methylates the host genome, providing self-immunity against this restrictase. Since they degrade only foreign DNA, R-M systems are proposed to antagonize transformation by DNA from other bacteria. The DpnII R-M system investigated in this study is present in around half of pneumococcal isolates tested and also possesses an unusual methylase of ssDNA, DpnA, which is specifically induced during the brief genetic transformation time window.

This study shows that DpnA gene is crucial for the exchange of pathogenicity islands when the foreign DNA is unmethylated (i.e., from a non-DpnII modified DNA donor). By methylating the internalized foreign ssDNA, DpnA protects the chromosome of those transformants that incorporate the foreign pathogenicity islands, such as the capsule locus. In the absence of this unique methylation, the novel transformant chromosomes would be degraded by the DpnII restrictase, thus forbidding the acceptance of the foreign DNA sequences.

The researchers found that the role of DpnA is to protect foreign DNA, allowing pathogenicity island exchange between bacteria. Jean-Pierre Claverys, Principal Investigator and senior author of the paper concludes that "this finding is the first evidence for a mechanism that actively promotes genetic diversity of S. pneumoniae through programmed protection and incorporation of foreign DNA."

###

Public Library of Science: http://www.plos.org

Thanks to Public Library of Science for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126846/Streptococcus_pneumonia_shields_foreign_DNA_derived_from_other_bacteria_to_promote_genetic_diversity_and_vaccine_evasion_

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Video: Ichan: I Don't Buy Things Just to Get Even

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Source: http://video.msnbc.msn.com/cnbc/50825444/

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Google Glass hackathon in pictures: geeks get coding on headgear of the future

You might remember that Google decided to host a little get together with those lucky "explorers" that pre-ordered Glass. Well, no one is allowed to tell us a darn thing about what went down thanks to those pesky NDAs the devs were required to sign. But, the folks at Mountain View didn't want us to feel completely left out, so they posted a bunch of pictures from the hackathons so we could get a glimpse at what it's like to be granted early access. Predictably, what you get is a bunch of geeks wearing computers while typing on computers. In total the "pioneers" built 80 new ways to use Glass, at least one of which we're sure involved viewing pornography (that's a right of passage for all new tech), and eight winning teams picked up the grand prize -- Google footing the bill for their Explorer Edition headset. We've got one more image after the break, but you can peruse the entire gallery at the source link.

Source: http://www.engadget.com/2013/02/15/dnp-google-glass-hackathon-in-pictures-geeks-don-more-functiona/

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Proteins Behind Mad-Cow Disease Also Help Brain to Develop

Prion proteins cause pathologies such as hamster scrapie when they misfold (right) ? but the same protein has benign functions when folded correctly (left). Image: N. Engl. J. Med. 344, 1516-1526 (2001)

Prions are best known as the infectious agents that cause ?mad cow? disease and the human versions of it, such as variant Creutzfeldt?Jakob Disease. But the proteins also have at least one known useful function, in the cells that insulate nerves, and are suspected to have more. Now researchers have provided the first direct evidence that the proteins play an important role in neurons themselves.

The team reports in the Journal of Neuroscience that prions are involved in developmental plasticity, the process by which the structure and function of neurons in the growing brain is shaped by experience.?

Prions come in two main forms: the normal version and the misfolded, infectious version. The normal version, known as cellular prion protein (or PrP^C), is present in every cell of the body and helps to maintain the myelin sheath in the cells that protect the nerves.

But the molecule is abundant in neurons themselves, especially during development. Because it is tethered to the membrane, it is widely assumed to be involved in signaling between nerve cells, but little direct evidence has been found for this.

Neurobiologist Enrico Cherubini of the International School for Advanced Studies in Trieste, Italy, and his colleagues therefore decided to look at the effects of electrical stimulation on slices of tissue from the hippocampus of healthy 3?7-day-old mice and of animals genetically engineered to lack the gene that encodes the prion protein.?

They used electrodes to stimulate individual cells at the same time as the networks of young neurons showed bursts of spontaneous electrical activity, or to simultaneously stimulate pairs of cells that are connected to each other.

In the tissue from healthy animals, both procedures strengthened the links between neurons, a phenomenon known as long-term potentiation.

In mice without the prion gene, however, the stimulation had the opposite effect. In these animals, the procedure induced long-term depression, or a weakening of neuronal connections.

Ups and downs
Further experiments revealed that the potentiation in mice with cellular prion protein was caused by activation of an enzyme called protein kinase A. In the absence of cellular prion protein, however, activation of a related enzyme, called protein lipase C, caused a long-term lowering of the neuron's activity.

?This shows that [the cellular prion protein] controls the direction of plasticity in the developing hippocampus,? says Cherubini, adding that he and his colleagues now want to identify the molecules that transfer the prion signal from the membrane into the cell. ?

Long-term potentiation in the hippocampus is thought to be crucial for learning and memory, but the importance of prions is still unknown, and Cherubini would like to investigate how the proteins are involved in behavior. He also speculates that prions have a similar role in other parts of the developing brain, such as the visual cortex, and in adults.

"The function of cellular prion protein is quite mysterious, but this convincingly demonstrates that it has a crucial role in strengthening synaptic connections within developing neural networks," says R. Douglas Fields, chief of the Neural Development and Plasticity Section at the National Institute for Child Health and Development in Bethesda, Maryland.

This article is reproduced with permission from the magazine Nature. The article was first published on February 14, 2013.

Source: http://rss.sciam.com/click.phdo?i=6c8eb432ce0fd45fcd14c8ee30aa1dff

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